В.И. Ильин

Аватар пользователя В.И. Ильин
Виктор
И.
Ильин
Место работы, город: 
Пардью Фарма, Крэнбери, Нью Джерси
Степень: 
к.б.н.
Должность, звание: 
директор по молеулярной фармакологии
Публикации: 

Kyle, D.J., and Ilyin, V.I. Sodium channel blockers. (2007) J. Med. Chem., 50, 2583-2588.

Benjamin, E.R., Pruthi, F., Olanrewaju, S., Shan, S., Lavery, D., Cerne, R., Woodward, R.M., Valenzano, K.J., and Ilyin, V.I. (2006) Pharmacological characterization of recombinant N-type calcium channel mediated calcium mobilization using FLIPR. Biochem. Pharmacol., 702, 770-782.

Ilyin, V.I., Pomonis, J.D., Whiteside, G.T., Harrison, J.E., Pearson, M.S., Mark, L., Turchin, P.I., Gottshall, S., Carter, R.B., Nguyen, P., Hogenkamp, D.J., Olanrewaju, S., Benjamin, E., and Woodward, R.M. (2006) Pharmacology of 2-[4-(4-chloro-2-fluorophenoxy)phenyl]-pyrimidine-4-carboxamide (PPPA): a potent, broad-spectrum state-dependent sodium channel blocker for treating pain states. JPET, 318 (3), p.1083-1093.

Benjamin, E.R., Pruthi, F., Olanrewaju, S., Ilyin, V.I., Crumley, G., Kutlina, E., Valenzano, K.J., and Woodward, R.M. (2006) State-dependent compound inhibition of Nav1.2 sodium channels using the FLIPR Vm dye: on-target and off-target effects of diverse pharmacological agents. J. Biomol. Screening, 11(1), p. 29-39.

Benjamin, E.R., Skelton, J., Hanway, D., Olanrewaju, S., Pruthi, F., Ilyin, V.I., Lavery, D., Victory, S.F., Valenzano, K.J. (2005). Validation of a fluorescent imaging plate reader membrane potential assay for high throughput screening of glycine transporter modulators. J. Biomol. Screening, 10 (4), p.365-373.

Ilyin, V.I., D.D. Hodges, E.R. Whitthemore, R.B. Carter, S.X. Cai, R. M. Woodward (2005). V102862 (Co 102862): a potent, broad-spectrum state-dependent blocker of mammalian voltage-gated sodium channels. Br. J. Pharmacol., v. 144, p. 801-812.

Wu, G., G.T. Whiteside, G. Lee, V.I. Ilyin. (2004). A-317491, a selective P2X3/P2X2/3 receptor antagonist, blocks nociceptor activation and sensitization by ab-methylene ATP in an inflamed rat skin-nerve preparation. Eur. J. Pharmacol., v. 504, p. 45-53.

Shao, B., S. Victory, V.I.  Ilyin, R.R. Goehring, Q. Sun, D. Hogenkamp, D.D. Hodges, K. Islam, D. Sha, C. Zhang, P. Nguyen, S. Robledo, G. Sakellaropoulos, R.B. Carter. (2004). Phenoxyphenyl pyridines as novel state-dependent, high-potency sodium channel inhibitors. J. Med. Chem., v.47 (17), p.4277-4285.

Yang, J., P. Gharagozloo, J. Yao, V.I. Ilyin, R.B. Carter, P. Nguyen, S. Robledo, R.M. Woodward, D.J. Hogenkamp. (2004). 3-(4-Phenoxyphenyl)pyrazoles: a novel class of sodium channel blockers. J. Med. Chem., v. 47, p. 1547-1552.

Hoger J.H., V.I. Ilyin, S. Forsyth, A. Hoger. (2002). Shear stress regulates the endothelial Kir2.1 ion channel. Proc. Natl. Acad. Sci. USA, v. 99, No 11, p. 7780-7785.

Область экспертизы: 

мембранная и клеточная биофизика, нейрофизиология, механизмы боли, электрофизиология, имиджинг, поиск новых лекарственных веществ